A cancer-wide analysis finds cancer-wide targets for tumor reduction NatureGenet
thanks Artem Babaian and the other, anonymous, reviewer for their contribution to the peer review of this work.Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations., Frequency of 26,816 TE-chimeric transcripts in 33 cancer types from TCGA. Each dot represents a separate sample, and the top of the graph lists the number of samples in each cancer type and the mean number of TE-chimeric transcripts for that cancer type.
17E-03, COAD-TP53: 3.15E-06, READ-TP53: 9.01E-04, STAD-TP53: 3.70E-02, HNSC-CASP8: 7.80E-04, HNSC-NOTCH1: 4.37E-02, HNSC-NSD1: 3.08E-04, BRCA-TP53: 4.37E-02, LIHC-TP53: 7.11E-03., Number of tumor and normal samples all TE-chimeric transcripts were present in. Those highlighted in blue passed our threshold for tumor-specificity. The bottom graph is a zoomed in on the section of the top graph that has a dotted box around it.
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