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In a world's first, surgeons at the Massachusetts General Hospital in Boston have transplanted a kidney from a gene-hacked pig into a living 62-year-old man.
Fortunately, the surgeons' efforts appear to have paid off — at least for now. The pig kidney started producing urine not long after the surgery last weekend, theIn fact, he's already walking the halls and could soon be discharged.
Yet only a tiny fraction of these patients end up receiving a kidney transplant, the best option for people suffering from end-stage kidney disease. For one, xenotransplanted organs still run the risk of being rejected by the recipient's immune system.The company used CRISPR-Cas9 gene editing to reduce the chances of the patient's body rejecting the new kidney and improve compatibility.reports, two experiments involving the xenotransplantation of pig hearts into patients with heart disease ended in the patients dying shortly afterward.
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