A large trial suggests that patients with preserved ejection fraction who have had smaller MIs may be able to skip beta-blockers after leaving the hospital.
, but people who have had smaller MIs and survive with preserved ejection fraction may be able to skip the beta-blockers and leave the hospital with one less prescription, a large, registry-based, open-label trial suggested.
After an average follow-up of 3.5 years, the rate of all-cause death or MI was 7.9% in the beta-blocker group and 8.3% in the no beta-blocker group, according to results presented at the "The standard is, you are healthy one day, then you have a small myocardial infarction, and you're put on at least five more medications. Patients always ask us, 'Do we really need five medications for this small incident'?"
Yndigegn acknowledged several limitations with the study. It was an open-label trial without blinding, the endpoints from registries were not reviewed for consistency, and it did not account for patients crossed over from one regimen to the other.
MI Preserved Ejection Fraction Beta-Blockers Trial Registry-Based Acute MI
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