Every disease is shaped by a genetic component as well as environmental factors like air pollution, climate and socioeconomic status.
Penn StateJul 30 2024 However, the extent to which genetics or environment plays a role in disease risk -; and how much can be attributed to each -; isn't well understood. As such, the actions individuals can take to reduce their risk for disease aren't often clear.
Bibo Jiang, assistant professor of public health sciences, Penn State College of Medicine and senior author of the study In this study, the team developed a spatial mixed linear effect model that incorporates both genetics and geolocation data. Geolocation -; a person's approximate geographical location -; served as a surrogate measure for community-level environmental risk factors.
"Previous studies concluded that genetics played a much larger role in disease risk prediction, and our study recalibrated those numbers," Liu said. "That means that people can stay hopeful even though they have family relatives with Type 2 diabetes, for example, because there's a lot they can do to reduce their own risk."
Air Pollution Artificial Intelligence Diabetes Genetic Genetics Health Insurance Medicine Pollution Public Health Research Students Type 2 Diabetes
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