People with alcohol use disorder and depression report high pleasure from drinking

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People with alcohol use disorder and depression report high pleasure from drinking
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A new study from the University of Chicago Medicine reveals that people with alcohol use disorder (AUD) and depression experience high levels of stimulation and pleasure when intoxicated, similar to drinkers who do not have depression.

University of ChicagoFeb 4 2025 A new study from the University of Chicago Medicine reveals that people with alcohol use disorder and depression experience high levels of stimulation and pleasure when intoxicated, similar to drinkers who do not have depression.

Andrea King, PhD, Professor of Psychiatry and Behavioral Neuroscience at UChicago and lead author of the study The effects of alcohol on the brain are complex, and improved understanding of the factors that affect an individual's vulnerability to AUD and depression is critical to identify and initiate early, effective treatment. However, few studies have examined how people with AUD respond to alcohol either in controlled laboratory settings or the natural environment; including individuals with AUD and another co-morbid diagnosis adds to the complexity.

"For nearly a decade, our group has been improving methods to use mobile technologies to measure real time clinically meaningful outcomes in people with AUD and those at risk for alcohol-related problems," said study co-author Daniel Fridberg, PhD, Associate Professor of Psychiatry and Behavioral Neuroscience at UChicago. "These approaches allow us to bridge the gap between the lab and real life and have led to new insights that could one day result in better treatments.

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