Acute graft-versus-host disease occurs when donor immune cells attack the recipient's tissues after an allogeneic hematopoietic stem cell transplantation (allo-HCT). Researchers recently identified a bacteriophage-derived enzyme called endolysin capable of targeting biofilms formed by Enterococcus faecalis.
Phage-derived enzyme targets E. faecalis biofilms to mitigate acute graft-versus-host disease." ScienceDaily. ScienceDaily, 11 July 2024. <www.sciencedaily.comThe Institute of Medical Science, The University of Tokyo. . Phage-derived enzyme targets E. faecalis biofilms to mitigate acute graft-versus-host disease.The Institute of Medical Science, The University of Tokyo."Phage-derived enzyme targets E. faecalis biofilms to mitigate acute graft-versus-host disease." ScienceDaily.
Clinicians have a new standard for graft-versus-host disease prevention after allogeneic hematopoietic stem cell transplantation, according to results from a phase III study. The new standard ... Researchers have identified a specific gut bacterium involved in the progression of graft-versus-host disease after antibiotic treatment of allogeneic hematopoietic stem cell transplantation ...
Researchers have shown that blocking IL-6 and TNF cytokines provides a more effective approach to preventing life-threatening graft-versus-host-disease, an inflammatory condition that develops in ... More than 40,000 allogeneic hematopoietic stem cell transplants are carried out worldwide every year, mostly for patients suffering from leukemia or other diseases of the hematopoietic system. Very ...Research on the Visual Rabbit Illusion Takes a Leap Forward
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Phage-derived enzyme targets E. faecalis biofilms to mitigate acute graft-versus-host diseaseAllogenic hematopoietic cell transplantation (allo-HCT) involves transferring healthy donor stem cells to recipients with conditions such as blood cancer, bone marrow failure, or certain genetic blood disorders. Acute graft-versus-host disease (aGVHD) is a common complication, where the donor's immune cells attack the recipient's tissues.
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Climate change and sea level rise pose an acute challenge for cities with combined sewer systemsOlder coastal cities, like Philadelphia, New York and Boston are at risk of being inundated by untreated sewage during floods. Due in part to the design of their combined sewer systems and in part due to sea level rise, these cities could be facing a growing public health crisis as climate change also drives more extreme precipitation.
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