Pharmaceutical Continuous Manufacturing vs. Batch Manufacturing: What's the Difference?

Pharmaceutical Continuous Manufacturing News

Pharmaceutical Continuous Manufacturing vs. Batch Manufacturing: What's the Difference?
Batch ManufacturingPharmaceutical Manufacturing
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Transitioning to continuous manufacturing enhances pharmaceutical production, reducing costs and improving quality through real-time monitoring and automation.

Advantages and disadvantages Historically, pharmaceutical products have been produced in a traditional ‘batch’ system, in which every operation is executed separately using a defined quantity of materials. In batch manufacturing processes, manufacturers can collect and evaluate intermediate products before continuing to the next phase1.

Advantages and disadvantages The aim of continuous manufacturing is to modernize the supply chain, enhance the robustness of the manufacturing process and thereby reduce product failures and enhance product quality3.” One of the key advantages associated with continuous manufacturing is the option to modify batch sizes by increasing run times; however, this modification requires the consideration of certain issues that may arise, such as equipment overheating or the accumulation of materials during longer runs.

Batch vs Continuous Manufacturing - Pharmaceutical IndustryPlay Industry trends and adoption Major regulatory agencies throughout the world have largely supported the implementation of continuous manufacturing technologies due to their numerous advantages. For example, although a robust control strategy must monitor both batch and continuous process manufacturing products, a performance-based control strategy is the optimal approach.

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