Sempra Energy Port Arthur LNG Phase 1 project is fully subscribed with long-term offtake agreements, following a supply deal with Poland for 1 million tonnes of liquefied natural gas per year. Construction on the project is set to begin later this quarter
Phase One Of Sempra’s Port Arthur LNG Project Is Now Fully SubscribedLos Angeles County Passes Ban On New Oil And Gas DrillingExxon Stops Flaring In The Permian, Urges Others To Follow SuitRising Crude, Gasoline Inventories Weigh On Oil PricesHalliburton Hikes Dividend By 33% After Earnings BeatGermany’s Electricity Subsidies Will Cost More Than $18 Billion Through MayOPEC+ Set To Keep Oil Production UnchangedEurope’s Gas Prices Slump By 11% On Warmer Weather ForecastsU.S.
Urges Azerbaijan To End Blockade At Lachin CorridorTexas Oil And Gas Tax Payments Broke Records In 2022$300 Million Fake Meat Fund Aims To Decarbonize The Food IndustryLiberty Steel Restructuring Sparks Output UncertaintyRussian Crude Exports from Baltic Ports See 50% Hike In JanuaryKuwait Cabinet Resigns Over Oil Wealth SpendingPoland Says It Will Deliver Leopard 2 Tanks With Or Without German GreenlightNetherlands To Shut Down Europe's Largest Gas FieldCalifornia City Gives Up On 100%...
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The persistent viral infections in the development and severity of myalgic encephalomyelitis/chronic fatigue syndrome - Journal of Translational MedicineBackground Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a multifactorial disease with an unexplained aetiology in which viral infections are possible trigger factors. The aim of this study was to determine the involvement of human herpesvirus (HHV)-6A/B, HHV-7, and parvovirus B19 (B19V) in the etiopathogenesis of ME/CFS. Methods 200 patients with clinically diagnosed ME/CFS and 150 apparently healthy individuals were enrolled in this study. Single-round, nested, and quantitative real-time polymerase chain reactions (PCR) were used to detect the presence and load of HHV-6A/B, HHV-7, and B19V. HHV-6A and HHV-6B were distinguished by PCR and restriction analysis. Immunoenzymatic assays were applied to estimate the presence of virus-specific antibodies and the level of cytokines. Results HHV-6A/B, HHV-7, and B19V specific antibodies were detected among patients and healthy individuals in 92.1% and 76.7%, 84.6% and 93.8%, and 78% and 67.4% of cases. HHV-6B had 99% of HHV-6 positive patients. Latent HHV-6A/B, HHV-7, and B19V infection/co-infection was observed in 51.5% of the patients and 76.7% of the healthy individuals, whereas active–45% of the ME/CFS patients and 8.7% of healthy individuals. HHV-6A/B load in patients with a persistent infection/co-infection in a latent and active phase was 262 and 653.2 copies/106 cells, whereas HHV-7 load was 166.5 and 248.5 copies/106 cells, and B19V-96.8 and 250.8 copies/106 cells, respectively. ME/CFS patients with persistent infection in an active phase had a higher level of pro-inflammatory cytokines (interleukin(IL)-6, tumor necrosis factor-alpha(TNF-α) and IL-12) and anti-inflammatory (IL-10) than with a persistent infection in a latent phase. A significant difference was revealed in the levels of TNF-α, IL-12, and IL-10 among the patient groups without infection, with latent infection/co-infection, active single, double and triple co-infection. The levels of TNF-α, IL-12, and IL-10 are significantly higher i
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