Finger-prick test developed for trichomoniasis
in our country and worldwide makes evident the need for a POC test that fulfills the WHO ASSURED criteria. This is especially highlighted by the chronic, subclinical adverse health outcomes for individuals with trichomoniasis. Equally significant are the findings of undiagnosed, persistentinfections and health disparities among subpopulations.
No. 10,386,369, “Strings of Epitopes Useful in Diagnosing and Eliciting Immune Responses to Sexually Transmitted Infections.” Inventor J.F. Alderete, Issued to Washington State University 20 August 2019. No. 10,677,798. Strings” of Epitopes Useful in Diagnosing and Eliciting Immune Responses to Sexually Transmitted Infections.” Inventor J.F. Alderete, Issued to Washington State University 9 June 2020.No. ZL02819646.5. Rapid Diagnostic Device and Assay. China.No. 7,531,362, Rapid Diagnostic Device, Assay and Multifunctional Buffer. United States.No. 8,586,375 . Rapid Diagnostic Device, Assay and Multifunctional Buffer. United States.
J.F.A.: Conceived and designed the experiments that led to identification of α-actinin as the diagnostic target. H.C.: Construct and apply the required biologics onto the RVF test platform that led to the development of the functional prototype for the detection of specific antibody against α-actinin in serum and blood specimens. Both J.F.A. and H.C.
No new data beyond what is presented in this paper were created or analyzed in this study. Data sharing is not applicable to this article.J.F.A.: I thank a past collaborator at Washington University at St. Louis for providing sera of men that was highly seropositive for α-actinin, and approval was obtained by the university Institutional Review Board. The sera of men were from the Health Professionals Follow-up Study, which began in 1986. Men sera were also from the Harvard T.H.