A study reveals that Mediterranean and green-MED diets rich in polyphenols may slow brain aging and reduce neurodegeneration through improved glycemic control.
By Dr. Chinta SidharthanReviewed by Lily Ramsey, LLMNov 6 2024 A new study suggests that Mediterranean and green-MED diets, rich in polyphenols from sources like green tea and Mankai, may slow brain aging and reduce neurodegeneration. Blood sugar control plays a key role in preserving brain volume.
Background The brain undergoes a natural process of shrinkage or atrophy with age, which is also linked to cognitive decline with progressing age. While the natural rate of brain atrophy with age is unavoidable, certain illnesses and conditions, such as type 2 diabetes, inflammation, high cholesterol, and high blood pressure, can accelerate the rate of cognitive impairment and brain atrophy.
About the study The present study was based on a previous randomized control trial of dietary interventions, known as the 18-month DIRECT PLUS trial, which was conducted in a workplace setting and enrolled close to 300 participants above the age of 30 years. Additionally, each group also received specific nutritional guidance and physical activity instructions, and each participant was provided with gym memberships and attended regular instructional sessions on exercise and nutrition.
In contrast, simple changes in weight did not have any pronounced impact on brain aging as compared to changes in glycemic control, suggesting an independent benefit on brain health from better glycemic control.
Polyphenol Aging Alzheimer's Disease Blood Blood Pressure Blood Sugar Cholesterol C-Reactive Protein Diabetes Diet Fasting Glucose Green Tea Hba1c High Blood Pressure High Cholesterol Inflammation Insulin Meat Mediterranean Diet Neurodegeneration Nutrition Protein Tea Type 2 Diabetes Vegetables
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