Potential liver risks from popular herbal supplements revealed in new study

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Potential liver risks from popular herbal supplements revealed in new study
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A study in JAMA Network Open reveals that 5% of U.S. adults consume six potentially hepatotoxic botanicals, highlighting a significant need for increased regulatory oversight.

By Dr. Sanchari Sinha Dutta, Ph.D.Aug 6 2024 A study published in JAMA Network Open reveals that about 5% of U.S. adults are exposed to six potentially hepatotoxic botanicals, which are largely unregulated products typically used to improve health or treat minor health complications.

Existing observational study findings indicate that the proportion of drug-induced liver injury cases from herbal and dietary supplements has increased from 7% in 2005 to 20% in 2014 in the United States. Related StoriesData from more than 9,500 US adults were analyzed in this study, which included prescription drug and herbal and dietary supplement exposure data in the past 30 days. The participants were enrolled in the NHANES between January 2017 and March 2020. Due to the COVID-19 pandemic, data collection for the NHANES 2019-2020 cycle was interrupted. Data from the 2020 U.S. Census was used to estimate the population size.

Regarding pre-existing health conditions, a significantly higher prevalence of hypertension, diabetes, coronary heart disease, stroke, arthritis, thyroid disorder, cancer, or liver complications was observed among herbal and dietary supplement users compared to that among non-users.

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