Researchers said the finding is ‘remarkable’.
Scientists have identified a gene missing in some people with obesity and postnatal depression, and have identified a potential cure
They found that the boys were both missing a single gene – known as TRPC5, which sits on the X chromosome. Female mice showed similar behaviours. And when they became mothers they also displayed depressive-like behaviour and “impaired care of offspring,” the authors said.One of our inspiring public health nurses sent us this 😊 😊“They displayed very similar behaviours to those seen in people missing the TRPC5 gene, which in mothers included signs of depression and a difficulty caring for their babies. This shows us that this gene is causing these behaviours.
In the latest study, researchers found that deleting the TRPC5 gene from these oxytocin neurons led to otherwise healthy mice showing signs of anxiety, overeating impaired social skills and, in the case of mothers, postnatal depression-like symptoms.This, the authors said, suggests that restoring oxytocin could help treat people with missing or defective TRPC5 genes – which could potentially lead to new treatments for obesity and postnatal depression.
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