Pregnant women at increased risk of COVID-19 severity UofT SARSCoV2 COVID19 COVIDSeverity Pregnancy
By Pooja Toshniwal PahariaJul 11 2022Reviewed by Aimee Molineux In a recent study published in Clinical Infectious Diseases, researchers assessed the severity of severe acute respiratory syndrome coronavirus 2 infections during pregnancy in Ontario, Canada.
The study was conducted between 1 January 2020 and 4 January 2022 to determine the relative risk of severe COVID-19 among SARS-CoV-2-positive pregnant females and SARS-CoV-2-positive females of reproductive age . A SARS-CoV-2 case file based on the population of Ontario was used for the analysis. Conditional and multivariable logistic regression modeling was used for determining the comparative risk of severe COVID-19 outcomes among the two study groups. Standardized morbidity ratios and adjusted odds ratios were calculated for the analysis. In addition, a restriction analysis was performed to evaluate the risk of ICU admissions among hospitalized cases and controls with data adjustments for vaccination, age, and comorbidities.
Substantially higher risks of hospital admissions and ICU admissions were observed among cases in comparison to controls; however, the differences between the above-mentioned risks among cases and controls were non-significant after data adjustments for age, the status of vaccination, causative SARS-CoV-2 variant and comorbidities .
United Kingdom Latest News, United Kingdom Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Covid-19 vaccines saved an estimated 20m lives during their first yearAs bad as the past 18 months have been, they would have been worse without vaccines—perhaps about 2.7 times worse
Read more »
Key characteristics impacting survival of COVID-19 extracorporeal membrane oxygenation - Critical CareBackground Severe COVID-19 induced acute respiratory distress syndrome (ARDS) often requires extracorporeal membrane oxygenation (ECMO). Recent German health insurance data revealed low ICU survival rates. Patient characteristics and experience of the ECMO center may determine intensive care unit (ICU) survival. The current study aimed to identify factors affecting ICU survival of COVID-19 ECMO patients. Methods 673 COVID-19 ARDS ECMO patients treated in 26 centers between January 1st 2020 and March 22nd 2021 were included. Data on clinical characteristics, adjunct therapies, complications, and outcome were documented. Block wise logistic regression analysis was applied to identify variables associated with ICU-survival. Results Most patients were between 50 and 70 years of age. PaO2/FiO2 ratio prior to ECMO was 72 mmHg (IQR: 58–99). ICU survival was 31.4%. Survival was significantly lower during the 2nd wave of the COVID-19 pandemic. A subgroup of 284 (42%) patients fulfilling modified EOLIA criteria had a higher survival (38%) (p = 0.0014, OR 0.64 (CI 0.41–0.99)). Survival differed between low, intermediate, and high-volume centers with 20%, 30%, and 38%, respectively (p = 0.0024). Treatment in high volume centers resulted in an odds ratio of 0.55 (CI 0.28–1.02) compared to low volume centers. Additional factors associated with survival were younger age, shorter time between intubation and ECMO initiation, BMI | 35 (compared to | 25), absence of renal replacement therapy or major bleeding/thromboembolic events. Conclusions Structural and patient-related factors, including age, comorbidities and ECMO case volume, determined the survival of COVID-19 ECMO. These factors combined with a more liberal ECMO indication during the 2nd wave may explain the reasonably overall low survival rate. Careful selection of patients and treatment in high volume ECMO centers was associated with higher odds of ICU survival. Trial registration Registered in the German Clinical Trials Re
Read more »
Covid-19 in the UKCovid infections in the UK have continued to rise, the latest weekly Office for National Statistics (ONS) figures suggest.
Read more »
Speaking COVID-19: supporting COVID-19 communication and engagement efforts with people from culturally and linguistically diverse communities - BMC Public HealthBackground Since the emergence of COVID-19, issues have been raised regarding the approach used to engage with Culturally and Linguistically Diverse (CaLD) communities during this public health crisis. This study aimed to understand the factors impacting communication and engagement efforts during the COVID-19 pandemic from the perspective of crucial CaLD community stakeholders and opinion leaders. Methods Forty-six semi-structured telephone interviews were undertaken with key stakeholders who have an active role (established before the pandemic) in delivering services and other social support to CaLD communities in Australia. Results Seven key themes emerged: (1) the digital divide and how to connect with people; (2) information voids being filled by international material; (3) Differentiating established with new and emerging communities’ needs; (4) speaking COVID-19; (5) ineffectiveness of direct translations of English language resources; (6) coordination is needed to avoid duplication and address gaps and (7) recognising the improvements in governments’ approach. Conclusion Alliances must be set up that can be activated in the future to reduce issues around resource development, translation, and dissemination of messages to minimise gaps in the response. Financial assistance must be provided in a timely way to community organisations to support the development and dissemination of culturally appropriate communication materials.
Read more »
Lorraine Kelly forced to miss ITV show after testing positive for Covid-19No Lorraine Kelly this morning as she tests positive for Covid-19 - We hope you get better soon Lorraine 💖
Read more »
How does the belief that vaccination will end the COVID-19 pandemic relate to vaccination intent?How does the belief that vaccination will end the COVID-19 pandemic relate to vaccination intent? CDCgov SARSCoV2 COVID19 Vaccination Vaccine Intent
Read more »