Researchers identify causal associations between artificial sweeteners and pregnancy outcomes.
By Dr. Liji Thomas, MDReviewed by Benedette Cuffari, M.Sc.Oct 8 2024 Artificial sweetener consumption may cause complications in pregnancy; however, this association remains unclear.
What are artificial sweeteners? ASs or non-nutritive sweeteners are sugar substitutes with high sweetness but low energy content. The use of ASs may reduce the incidence of dental caries and obesity, thus making these sweeteners an attractive option for people with type 2 diabetes mellitus . About 33% of pregnant women in the Randomized Control Trial of Low Glycemic Index Diet in Pregnancy to Prevent Recurrence of Macrosomia reported the consumption of ASs during each trimester, over 51% of whom continued to consume ASs when advised to maintain a low-glycemic index diet. In fact, pregnant women may be even more likely to use ASs than the general population.
The aim of the current study was to identify the presence and significance of causality in any observed associations between AS exposure and APOs. To this end, genome-wide association study data were obtained from the publicly available IEU Open GWAS Project. Multiple analytic methods were used to examine the presence and significance of correlations between AS intake and pregnancy outcomes.
Pregnancy Coffee Diabetes Diabetes Mellitus Diet Eclampsia Ectopic Pregnancy Genetic Gestational Diabetes Glucose Glycemic Index Nutrients Obesity Placenta Pre-Eclampsia Research Tea Type 2 Diabetes
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