Karl Klose, director of The South Texas Center for Emerging Infectious Diseases (STCEID) and the Robert J. Kleberg, Jr. and Helen C. Kleberg College of Sciences Endowed Professor, coauthored a research article with Cameron Lloyd '23, a UTSA doctoral student who graduated in August with a Ph.D.
Reviewed by Danielle Ellis, B.Sc.Nov 7 2023 in molecular microbiology and immunology under the guidance of Klose.
V. cholerae choleraeis found naturally on various surfaces within marine environments. When water or food contaminated with V. cholerae is consumed by humans, it colonizes the gastrointestinal tract and causes cholera. He learned how to study V. cholerae, genetically manipulate the bacteria, and measure its ability to spread disease, bind to red blood cells and form biofilms, which are surfaces where communities of bacteria form that are more resistant to antibiotics. Lloyd is currently interviewing for several postdoctoral fellowship positions in laboratories across the nation.
Related Stories"We demonstrated that these peptide inhibitors could inhibit both biofilm formation as well as intestinal colonization by V. cholerae," said Klose. "It is possible that this could be part of intervention strategies to inhibit these bacteria from causing disease and persisting in the environment."
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