Research looks to determine prevalence of organ impairment in long-COVID patients Research Coronavirus Disease COVID19 LongCOVID PASC editorjrsm LivUni UniOfHull UniofOxford ucl
There are well-known symptoms of long COVID or post-acute sequelae of COVID-19. However, there is little description of its natural history, based either on symptoms, organ dysfunction, or functioning. Long COVID may be associated with the severity of initial disorders in some hospitalized patients; however, prognostic variables in non-hospitalized patients are neither defined nor examined systematically.
The study involved patients diagnosed with COVID-19 who did not have any active severe acute respiratory syndrome coronavirus 2 infection but continued to display related symptoms. A retrospective review of the duration of symptoms characterized the persons experiencing long COVID based on persistent symptoms noted for 12 weeks. Those with signs of organ impairment detected based on blood tests, magnetic resonance imaging , or incidental findings were examined at a six-month follow-up visit.
Results At baseline, a total of 536 participants were included. At baseline, all patients in the group were symptomatic. Women and obese persons were more likely to have systemic or cardiopulmonary symptoms or poor HRQoL. Participants from the follow-up cohort displayed a median of 10 symptoms at baseline and three symptoms at follow-up.
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