Due to the high transparency of cells, it is very difficult to observe the organelles within them. Biologists can label specific organelles for observation through fluorescence staining. This is somewhat analogous to being in an environment without light where everyone is dressed entirely in black, making it difficult to find your friends.
Research presents 2D dipole orientation method for mapping cells retrieved 9 May 2024 from https://phys.org/news/2024-05-2d-dipole-method-cells.html
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