Advanced research is casting light on possible early life factors – including poverty, physical or mental abuse – that may impact the rate of egg loss and increase the risk of cardiovascular disease in post-menopausal women.
Traditionally, cardiovascular disease in women has been associated with loss of ovarian function with the transition into the non-reproductive years.
A major medical conference in South Australia heard today that cardiovascular disease risk is increasing in women, along with earlier age at onset, while it is decreasing in men. Women who experience early menopause, say in their forties, are at a much higher risk of developing heart disease later in life compared with women who go through natural menopause in their fifties and later.
Professor Cedars, who is also Immediate Past President of the American Society for Reproductive Medicine, said women have unique sex-specific risk factors for the condition that can appear early in their childhood and reproductive life. Professor Cedars said early life indicators of vulnerability required further research as they may provide a window into future cardiovascular health and cellular aging processes.
Professor Cedars said the fact that cardiovascular disease in women was increasing while it was decreasing in men suggests the need to investigate female-specific causes of aging and increased risk.
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