In a paper published today in Science Translational Medicine, researchers from City of Hope, one of the largest cancer research and treatment organizations in the United States and a leading research center for diabetes and other life-threatening illnesses, report that they have discovered advances in predicting kidney failure in type 1 diabetes...
May 22 2024City of Hope In a paper published today in Science Translational Medicine , researchers from City of Hope®, one of the largest cancer research and treatment organizations in the United States and a leading research center for diabetes and other life-threatening illnesses, report that they have discovered advances in predicting kidney failure in type 1 diabetes patients.
"It is therefore critical to find mechanisms leading to kidney failure in diabetes, as well as biomarkers of early detection to facilitate prompt intervention," said Natarajan, who is a corresponding author on the paper and a pioneer in diabetes epigenetics. "Where we were able to pinpoint key locations of kidney failure-associated DNA methylation variations, these biomarkers remained remarkably stable in the same person with T1D over several years," said Natarajan, the National Business Products Industry Endowed Chair in Diabetes Research.
Nancy Chen, M.D., M.S., paper's first author and assistant research professor in City of Hope's Department of Diabetes Complications & Metabolism
Kidney Kidney Failure Type 1 Diabetes Blood Cancer Dialysis DNA DNA Methylation Epigenetics Gene Gene Expression Genomic Kidney Disease Medicine Metabolism Ph Research
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