In one of the largest studies of cancer susceptibility across bird species, researchers describe an intriguing relationship between reproductive rates and cancer susceptibility.
In one of the largest studies of cancer susceptibility across bird species, researchers at Arizona State University describe an intriguing relationship between reproductive rates and cancer susceptibility.
"Birds are exceptional for many reasons but one of them is the fact that birds get less cancer than mammals, and we don't know why," says Carlo Maley, corresponding author of the new study."We'd like to understand how birds avoid getting cancer and see if we can use that to help prevent cancer in humans."
Such studies also help to explain why some long-lived species, which tend to have fewer offspring and invest more in maintenance and longevity, might have lower cancer rates. In contrast, species with high reproductive rates and shorter lifespans may prioritize reproduction over longevity and maintenance, increasing their vulnerability to cancer.
In earlier research, Maley and his colleagues explored how large mammals, including whales and elephants, have developed sophisticated strategies of cancer suppression, which may hold clues in the battle against human cancers. The research demonstrates the value of applying evolutionary thinking to cancer biology. By studying how different species manage the risk of cancer, researchers may uncover new strategies for prevention and treatment that could benefit both human and veterinary medicine.
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