Science, Space and Technology News 2024
A study found sex differences in brain pathways involved in reward-related behaviors. Understanding these differences may lead to better treatments for mental health disorders.
Although this is changing, historically, much more research has been done on male subjects , so “we just don’t know a lot about female brains and differences between male and female brains,” says Tara LeGates, assistant professor of biological sciences at the University of Maryland, Baltimore County and senior author on the new paper.
LeGates and lead author Ashley Copenhaver, a Ph.D. candidate in LeGates’ research group, found that mice of both sexes relied on activation of a particular kinase protein, CAMKII, to facilitate reward-related behavior. Neither sex requiredreceptor NMDA is also commonly involved in reward pathways and strengthening connections between brain regions.
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