Researchers listen in on how fat cells “talk” to the brain

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Researchers listen in on how fat cells “talk” to the brain
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News-Medical speaks to liye_tsri from scrippsresearch about his latest research which identified sensory neurons that carry a stream of messages from adipose tissue to the brain brain neurons adiposetissue sensoryneuron

Interview conducted by Danielle Ellis, B.Sc.Oct 5 2022 Thought LeadersLi Ye, PhDThe Abide-Vividion Chair in Chemistry and Chemical Biology and Associate ProfessorScripps Research

Why have attempts to study the types and functions of these neurons been difficult? It has been difficult because these neurons are deep in the body and intertwined with other neurons that innervate the skin and muscles. Our findings suggest that the sensory neurons and sympathetic neurons might have two opposing functions, with sympathetic neurons needed to turn on fat burning and the production of heat and sensory neurons required to turn these programs down.

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