Respiratory allergies: Newly discovered molecule plays a major role in triggering inflammation

Allergy News

Respiratory allergies: Newly discovered molecule plays a major role in triggering inflammation
AsthmaImmune SystemLung Disease
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One of the molecules responsible for triggering the inflammation that causes allergic respiratory diseases, such as asthma and allergic rhinitis, has just been discovered. This molecule, from the alarmin family, represents a therapeutic target of major interest for the treatment of allergic diseases.

One of the molecules responsible for triggering the inflammation that causes allergic respiratory diseases, such as asthma and allergic rhinitis, has just been discovered by scientists from the CNRS, Inserm and the Université Toulouse III -- Paul Sabatier. This molecule, from the alarmin family, represents a therapeutic target of major interest for the treatment of allergic diseases.

Alarmins, therefore, constitute major therapeutic targets for the treatment of respiratory allergic diseases. In a few years' time, treatments based on antibodies blocking the TL1A alarmin could benefit patients suffering from severe asthma or other allergic diseases. In France, at least 17 million people are affected by allergic diseaseswith the most severe forms of asthma being responsible for several hundred deaths every year.

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