Science, Space and Technology News 2024
Researchers at Johns Hopkins University discovered that an enzyme from fruit fly testes, previously thought to be involved in thyroid hormone regulation, plays a crucial role in controlling spermatogenesis. This finding offers a new approach to pest control, potentially affecting the fertility of disease-carrying and crop-damaging insects. Credit: SciTechDaily.com
Rokita’s group stumbled upon the discovery while studying how iodide works in the thyroid gland.
By removing and dissecting the testes of fruit flies, the team tracked how the enzyme regulates bromotyrosine levels. When they turned off the specific gene responsible for the enzyme, they saw bromotyrosine build up in the fruit fly testes.“It turns out that if the enzyme is lacking, bromotyrosine accumulates in male fruit flies, and that overload severely inhibits spermatogenesis,” Rokita said. “All flies have a similar gene, which means they might react to bromotyrosine in a similar way.
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