In this interview, NewsMedical speaks to DeNovix's Dan Schieffer about the new app developed for CellDrop, and how it aims to revolutionize hepatocyte count for the drug discovery industry, and more.
Sponsored Content by DeNovix Inc.Reviewed by Louis CastelJul 29 2024 insights from industryDan SchiefferScientific DirectorDeNovix Could you start by giving us an overview of the new CellDrop app and its significance in the realm of hepatocyte analysis? The Hepatocyte app on the latest version of CellDrop software is the first automated cell counter algorithm designed specifically to count hepatocytes .
Then, we added the CellDrop’s dual channel fluorescence capabilities to the algorithm to better distinguish live vs dead and debris vs cells. Could you discuss the app’s potential applications in drug discovery, toxicology, and virology research and how it might change the landscape in these fields? Cell counts need to be very accurate and consistent in these workflows where you are using liver models to study the effect of a drug or pathogen.
What has been the initial feedback from early users of the app, and how has this influenced any further development? It was quite exciting and a little stressful the first time I took the Hepatocyte app out in the field for a real beta test. Luckily, we had help from a lot of good scientists refining the algorithm along the way, and the lab was thrilled with the results.
Before I started working at DeNovix, I spent a lot of time in graduate school in labs working as a researcher. Cell counting sounds simple, but everybody does it differently. As people work through complicated workflows, we can confirm that they got their cell count right. Helping people like this is really rewarding to me.
Cell Counting Fluorescence Laboratory Life Science Liver Machine Learning Microscope Research Software Technology Trypan Blue
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