Australian researchers have discovered a previously unknown rogue immune cell that can cause poor antibody responses in chronic viral infections.
Apr 9 2024Monash University The finding, published today in the journal, Immunity , may lead to earlier intervention and possibly prevention of some types of viral infections such as HIV or hepatitis.
Researchers from the Monash University Biomedicine Discovery Institute have essentially solved this mystery by discovering how chronic viral infection induces a previously unknown immune B memory cell that does not produce high levels of antibody. What we discovered was a previously unknown cell that is produced by chronic viral infection. We also determined that early intervention with therapeutics was the most effective to stop this type of memory cell being formed, whereas late intervention could not." According to Dr Cooper, chronic viral infections have been known to alter our ability to form effective long-term protective antibody responses, but how that happens is unknown.
Antibody B Cell Cell Hepatitis HIV Immune System Immunity Research Therapeutics
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