Roman skeleton helps trace deadly malaria’s ancient roots

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Roman skeleton helps trace deadly malaria’s ancient roots
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Five malaria-causing species are believed to have originated in Africa 50,000 – 60,000 years ago before spreading globally.

3D illustration showing malaria parasite Plasmodium falciparum in schizont stage inside red blood cells, the causative agent of tropical malaria.In an effort to better understand Malaria’s complex history, scientists have successfully sequenced the mitochondrial genome of one of the deadliest forms of malaria. By using a remarkably well-preserved Roman skeleton, the researchers hoped to discover valuable insights into the disease’s complex history within Europe.

”in Barcelona, explains the intense co-evolutionary pressure between malaria and humanity: “With the development of treatments such as quinine in the last hundreds of years, it seems clear are co-evolving. Discovering the genomes of the ancient, pre-quinine plasmodia will likely reveal information about how they have adapted to the different anti-malarial drugs.”exist, believed to have originated in Africa 50,000 – 60,000 years ago before spreading globally.

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