De-extinction startup Colossal Biosciences claims it has found a way to reprogram elephant cells, a technical breakthrough that could lead to the return of the long-lost mammals.
De-extinction startup Colossal Biosciences wants to bring back the woolly mammoth. Well, not the woolly mammoth exactly, but an Asian elephant gene-edited to give it the fuzzy hair and layer of blubber that allowed its close relative to thrive in sub-zero environments.
Since cancer can be caused by genetic mutations that accumulate as cells divide, you’d expect that animals with 100 times more cells than humans would have a much higher risk of cancer. But elephants have cancer rates even lower than humans—a surprising fact given their vast size. One hypothesis for elephants’ cancer-defying biology is that they carry lots of copies of a tumor-suppressing gene called P53. Humans, on the other hand, only have one copy of this gene.
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