Scientists Discover Key to Unlocking the Secret of Degenerative Brain Disorders Like Alzheimer’s

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Scientists Discover Key to Unlocking the Secret of Degenerative Brain Disorders Like Alzheimer’s
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Science, Space and Technology News 2024

The development of NeuM, a novel neuron labeling technology, represents a major step forward in the fight against neurodegenerative diseases. By enabling selective labeling and high-resolution imaging of neuronal membranes, NeuM facilitates the detailed study of neuron structures and their changes over time.

Researchers from Dr. Kim Yoon-kyung’s team at KIST are utilizing the next-generation neuron labeling technology, ‘NeuM,’ to visualize neurons in real-time and examine high-resolution images. Credit: Korea Institute of Science and Technology NeuM, as the first technology to stain cell membranes through endocytosis in living neurons, exhibits selective reactivity towards living cells, excluding dead cells without internalization. Moreover, the research team has succeeded in extending the observation time of neurons from a mere 6 hours to up to 72 hours, enabling the capture of dynamic changes in living neurons over an extended period in response to environmental changes.

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