Scientists uncover possible neural link between early life trauma and binge-eatingdisorder NatureNeuro
Now, a Virginia Tech scientist has identified how early life trauma may change the brain to increase the risk of binge eating later in life.
"This finding speaks to a set of broader health questions, which is how life's health course is set based on certain early experiences," said Michael Friedlander, executive director of the Fralin Biomedical Research Institute at VTC and Virginia Tech's vice president for Health Sciences and Technology.
To identify the connection between the disorder and early life trauma, Shin and her lab team studied the impact of a hormone in the brain called leptin. Leptin has long been known suppress appetite andThe team found that in mice that experienced early life stress and exhibited behavior similar to binge-eating, leptin is less effective in a part of the brain called the lateral hypothalamus, where many behaviors are regulated. Without these signals from the brain, the overeating continues.
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