Sea urchins made to order: Scripps scientists make transgenic breakthrough

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Sea urchins made to order: Scripps scientists make transgenic breakthrough
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A success at Scripps in San Diego means scientists can run experiments on painted sea urchins, potentially unlocking new discoveries in biology.

Consider the sea urchin. Specifically, the painted urchin: Lytechinus pictus, a prickly Ping-Pong ball from the eastern Pacific Ocean. The species is a smaller and shorter-spined cousin of the purple urchins devouring kelp forests. They produce massive numbers of sperm and eggs that fertilize outside of their bodies, allowing scientists to watch the process of urchin creation up close and at scale. One generation gives rise to the next in four to six months.

has been snipped. acts like a bouncer, Hamdoun explained, parking along the cell membrane and ejecting foreign molecules. The protein's action can preserve the cell from harmful substances but can sometimes work against an organism’s best interest, as when it prevents the cell from absorbing a necessary medication.

. They can reverse-engineer how big a role plays in preventing a cell from absorbing a drug. And then there are the fluorescent urchins. “The magic happens in this room,” Jackson said, walking into a narrow office with $1 million worth of microscopes at one end and a decades-old hand-cranked centrifuge bolted to a table at another. He placed a petri dish containing three pencil-eraser-size transgenic urchins under a microscope.

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