Study reveals that both low and high levels of selenium and manganese in the blood are associated with increased mortality in adults with asthma, highlighting the importance of maintaining optimal levels of these metals.
By Dr. Sanchari Sinha Dutta, Ph.D.Sep 5 2024 Unveiling a delicate balance: New research shows that both too much and too little selenium and manganese in the blood can sharply increase the risk of death in asthma patients. Study: Association between blood heavy metal element and all-cause mortality in asthmatic adults: a cohort study. Image Credit: WESTOCK PRODUCTIONS / Shutterstock
Selenium is a micronutrient that plays a vital role in reducing oxidative stress and improving immune response. It has a multifactorial relationship with respiratory diseases, including asthma. Existing evidence indicates that low blood levels of selenium increase the risk of developing asthma; however, both deficient and excessive levels of selenium can be harmful.
They determined the survival status of participants by matching survey data with the National Death Index as of December 31, 2018. They also used the 10th edition of the International Statistical Classification of Diseases ten to determine the all-cause mortality status. Regarding other tested heavy metals , the study suggested possible relationships between these metals and mortality in initial analyses. However, these associations did not remain significant in the final multivariate analysis, indicating that their effects may be masked by confounding factors or require more complex mechanisms to explain.
Manganese Mortality Selenium Airway Inflammation Blood Breathing Bronchospasm Coughing Food Inflammation Lungs Oxidative Stress Research Respiratory Respiratory Disease Smoking Stress Tobacco
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