A new study published in the Proceedings of the National Academy of Sciences reveals that Sherpas demonstrate superior kidney adaptation to high altitude compared to lowlanders. The research, conducted by a team from Mount Royal University, focused on the blood acid-base acclimatization responses of both groups during an incremental ascent to 4,300 meters in the Nepal Himalaya.
Mount Royal UniversityDec 30 2024 A study from a Mount Royal University physiologist and his team demonstrates the key role of the kidneys in acclimatization to high altitude, and illustrates another way that Sherpas are better adapted to high altitude ascent.
The paper, "Comparing integrative ventilatory and renal acid-base acclimatization in lowlanders and Tibetan highlanders during ascent to 4,300 m", describes findings from an international high altitude research expedition to the Nepal Himalaya, funded by NSF and NSERC , where the team led by Dr. Trevor Day, PhD, studied the blood acid-base acclimatization responses to incremental ascent in lowlanders and Tibetan highlanders .
With so many people now living and traveling to high altitudes, understanding integrated acclimatization and adaptation to high altitude in human populations is of increasing importance, particularly comparing lowlander to highlander populations." High altitude exposure imposes a blood oxygenation and acid–base challenge, compensated by respiratory and renal acclimatization.
Health HIGH ALTITUDE SHERPAS KIDNEYS ACCLIMATIZATION PHYSIOLOGY
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