Single-cell multi-omics profiling links dynamic DNA methylation to cell fate decisions during mouse early organogenesis - Genome Biology

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Single-cell multi-omics profiling links dynamic DNA methylation to cell fate decisions during mouse early organogenesis - Genome Biology
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A study published in GenomeBiology presents an analysis of the effects of perturbing DNA methylation on mouse organogenesis at a whole organism scale.

The following sources of funding are gratefully acknowledged. This work was supported by the Wellcome Trust and the BBSRC . T.L. was funded by the Wellcome Trust 4-Year PhD Programme in Stem Cell Biology and Medicine and the University of Cambridge, UK . J.N. was supported by core funding by the MRC and Wellcome Trust to the Wellcome–MRC Cambridge Stem Cell Institute.

Wellcome Trust – Medical Research Council Stem Cell Institute, University of Cambridge, Jeffrey Cheah Biomedical Centre, Puddicombe Way, Cambridge, CB2 0AW, UKBioinformatics Group, Babraham Institute, Cambridge, CB22 3AT, UKDepartment of Haematology, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UKJohn C. Marioni

European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Cambridge, UKJohn C. Marioni & Wolf Reik Department of Physiology, Development and Neuroscience, University of Cambridge, Tennis Court Road, Cambridge, CB2 3EG, UKCurrent address: MRC Human Genetics Unit, University of Edinburgh, Crewe Road, Edinburgh, EH4 2XU, UK

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