A skin biopsy that can detect an abnormal protein in cutaneous nerve fibers holds promise for early detection of Parkinson's and other neurodegenerative disorders.
test is able to detect an abnormal form of alpha-synuclein with high accuracy in individuals with neurodegenerative disorders such as
He explained that patients often experience delays in diagnosis or are misdiagnosed due to the complexity of synucleinopathies. The study included 428 adults aged 40-99 years recruited from 30 academic and community-based neurology practices across the United States, with 277 diagnosed with PD, DLB, MSA, or PAF. It also included a control group of 120 participants with no symptoms suggestive of synucleinopathy.
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