Specific redox protein identified as a critical regulator of ferroptosis

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Specific redox protein identified as a critical regulator of ferroptosis
CancerFerroptosisProtein
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Researchers at Helmholtz Munich, in collaboration with colleagues at Tohoku University, have identified a specific redox protein as a critical regulator of ferroptosis - a form of regulated oxidative cell death.

Tohoku UniversityNov 15 2024

The team found that peroxiredoxin 6 serves as a critical regulator of ferroptosis and acts as a selenium carrier protein, playing an essential role in cellular defense against oxidative stress. Their findings suggest that PRDX6 could become an important target for treating cancer and neurodegenerative diseases.The team was led by Dr.

PRDX6 is a selenium carrier protein whose molecular identity had long been hypothesized but not identified."

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Cancer Ferroptosis Protein Selenium Cell Cell Death Metabolism Multiple Sclerosis Neurodegenerative Disease Neurodegenerative Diseases Research Sclerosis Tumor

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