A first-in-human trial suggests that neural stem cell transplant is safe, improves motor function, and provides hope for patients with chronic ischemic stroke.
CHICAGO — Early results from a first-in-human trial some 20 years in the making suggest that neural stem cell transplantation is safe and improves motor function starting at 1 month after treatment in patients with chronic
The 18 patients were aged 18-75 years and were 6 months to 5 years out from an ischemic subcortical middle cerebral stroke. They had a modified Rankin score of 3-4 and stable motor deficit, and they had been through rehabilitation. Patients with a stroke lesion 100 cc on MRI were excluded. Surprisingly, there was no correlation between clinical response and dose, age, sex, time of stroke to transplant, or stroke volume, Steinberg said.
"You don't need the cells to survive long term. They just need to release their factors stimulate this system. They jazz up the circuits, and now the circuits function again. It may be very important to combine it with physical therapy, as thein most patients, nausea, fatigue, transient worsened speech in three patients, and asymptomatic chronic subdural hygroma in two patients.
Transplantation Of Hematopoietic Stem Cells Hematopoietic Stem Cell Transplant Stem Cell Transplantation Stem Cell Therapy Stem Cell Haematopoietic Stem Cell Transplant HSCT Hematopoietic Stem Cell Transplantation (HSCT) Haematopoietic Stem Cell Transplantation (HSCT) HSCT - Hematopoietic Stem Cell Transplantation
United Kingdom Latest News, United Kingdom Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
This Startup Wants To Be OpenAI Of Stem Cell Therapy, Targets $250B MarketI'm Managing Partner at gPress, a marketing, publishing, research and education consultancy. Previously, I held senior marketing and research management positions at NORC, DEC and EMC.
Read more »
Using stem cell-derived heart muscle cells to advance heart regenerative therapyRegenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function. However, the risk of arrhythmias following this procedure is reportedly high.
Read more »
T cell lymphoma and secondary primary malignancy risk after commercial CAR T cell therapyWe report a T cell lymphoma (TCL) occurring 3 months after anti-CD19 chimeric antigen receptor (CAR) T cell immunotherapy for non-Hodgkin B cell lymphoma. The TCL was diagnosed from a thoracic lymph node upon surgery for lung cancer. The TCL exhibited CD8+ cytotoxic phenotype and a JAK3 variant, while the CAR transgene was very low.
Read more »
Counselors at STEM School Highlands Ranch continue the message of 'STEM Strong' 5 years after shootingNicole Brady is a Denver7 weekday morning anchor.
Read more »
Drug Prototype Shows Promise for Stem Cell Treatment of Pulmonary DiseaseProof-of-concept study supported potential of drug-like small molecule to promote lung tissue repair.
Read more »
Stem Cell Magic: Scientists Unveil New Superhero for Healing Diabetes WoundsScience, Space and Technology News 2024
Read more »