Strep A antibiotics in short supply, warn pharmacists as death toll in children hits 16
ANTIBIOTIC supplies for Strep A are going from bad to worse, warn pharmacists, while a probe has been launched into rocketing prices.
Antibiotic supplies for Strep A are going from bad to worse, warn pharmacistsDr Leyla Hannbeck, of the Association of Independent Multiple Pharmacies, said stocks of antibiotics are “poor”.The Competition and Markets Authority is investigating after some suppliers upped the cost from £2 per pack to £11.
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Effect of inpatient antibiotic treatment among older adults with delirium found with a positive urinalysis: a health record review - BMC GeriatricsBackground Among older adults with delirium and positive urinalysis, antibiotic treatment for urinary tract infection is common practice, but unsupported by literature or guidelines. We sought to: i) determine the rate of antibiotic treatment and the proportion of asymptomatic patients (other than delirium) in this patient population, and ii) examine the effect of antibiotic treatment on delirium resolution and adverse outcomes. Methods A health record review was conducted at a tertiary academic centre from January to December 2020. Inclusion criteria were age ≥ 65, positive delirium screening assessment, positive urinalysis, and admission to general medical units. Outcomes included rates of antibiotic treatment, delirium on day 7 of admission, and 30-day adverse outcomes. We compared delirium and adverse outcome rates in antibiotic-treated vs. non-treated groups. We conducted subgroup analyses among asymptomatic patients. Results We included 150 patients (57% female, mean age 85.4 years). Antibiotics were given to 86%. The asymptomatic subgroup (delirium without urinary symptoms or fever) comprised 38% and antibiotic treatment rate in this subgroup was 68%. There was no significant difference in delirium rate on day 7 between antibiotic-treated vs. non-treated groups, (entire cohort RR 0.94 [0.41–2.16] and asymptomatic subgroup RR 0.69 [0.22–2.15]) or in 30-day adverse outcomes. Conclusions Older adults with delirium and positive urinalysis in general medical inpatient units were frequently treated with antibiotics – often despite the absence of urinary or other infectious symptoms. We failed to find evidence that antibiotic treatment in this population is associated with delirium resolution on day 7 of admission.
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Surge in demand for Strep A antibiotics in Shropshire causes 'short-term' shortageOne superintendent pharmacist said: 'The system is struggling to keep up. There are two types of penicillin used to treat Strep A and it has all been out of stock.'
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