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Stressful life events, such as the death of a loved one or divorce, put a person at greater risk of developing dementia in later life, aThey took spinal fluid samples of a subset of the group to look for abnormal proteins – called amyloid and tau – that are associated with
The presence of markers of Alzheimer's disease could indicate that childhood and midlife are periods where the effects of stress in terms of chemicals and responses in the brain are particularly strong.Midlife is the time when Alzheimer's biomarkers start to accrue in the brain, so this could be why this is a vulnerable time, too.
The researchers also looked at the differences between men and women in the relationships between stressful life events and biomarkers of Alzheimer's. Total stressful life events were associated with reduced grey matter in women, but not men. In contrast, total stressful life events were associated with tau biomarkers in men but not women.both psychologically and biologically.
Also, we cannot be sure who developed Alzheimer's symptoms. The study only reports early physical markers of the disease, not diagnosis.Unfortunately, we cannot ensure that no one is exposed to stressful life events, but we can focus on how we can reduce the negative effects of these experiences. This could be done in a variety of ways.
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