Study assesses the value of predictive biomarkers for early-stage COVID-19 infection HealthcareMDPI_ biomarker COVID19 coronavirus covid infection
By Susha Cheriyedath, M.Sc.Aug 2 2023Reviewed by Sophia Coveney In a recent study published in the journal Healthcare, researchers illustrated that certain biomarkers may be better predictors of coronavirus disease 2019 than others.
Common biomarkers include C-reactive protein and complete blood cell count parameters, which are laboratory diagnosis standards and may be more useful in predicting disease progression. This raised concerns about whether COVID-19-positive patients were receiving corticosteroid therapy and the dosing regimen used in many studies. The present study examines whether baseline biomarkers and CRP levels can predict the development of pneumonia and the need for hospitalization with oxygen therapy prior to treatment interference.
All hospitalized patients had a SpO2 below 94% in room air, a respiratory rate greater than 30 breaths per minute, and radiographic evidence of pneumonia, rendering them gravely ill. Using Statistical Package for the Social Sciences , chi-square, and Mann-Whitney U tests, the data were analyzed for group comparison.
The study observed that those diagnosed with pneumonia displayed decreased levels of EOS and PLT, along with increased age groups, CRP, and NEU counts, in comparison to individuals without pneumonia. No apparent correlation between gender and pneumonia was observed.
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