Study finds connection between gut microbiome and bone density

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Study finds connection between gut microbiome and bone density
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There is growing evidence that a relative abundance of certain gut microbes may be related to skeletal health, according to a new study published in Frontiers in Endocrinology. If confirmed by additional research, the findings could provide the opportunity to alter gut microbiomes to achieve better bone health, as scientists learn more about 'osteomicrobiology,' a new term recently used to characterize this relationship.

Microbiome diversity of the two cohorts. Both cohorts were separately evaluated for microbial composition and diversity. In each cohort, taxa abundances were glomed at the genus level.

, non-metric multidimensional scaling was used to ordinate the data, using Bray-Curtis distance as the beta diversity metric . Cohort explained 3.0% of the total variability in the microbial abundance profiles . We adjusted for all covariates in the PERMANOVA test. Credit:There is growing evidence that a relative abundance of certain gut microbes may be related to skeletal health, according to a new study published in.

," the study found that bacteria called Akkermansia, which has been associated with obesity, and Clostridiales bacterium DTU089, had negative associations with bone health for older adults. "We found patterns in which greater abundance of microbiota were associated with worse measures of bone density and microarchitecture. In fact, some bacteria were associated with differences in the bone cross sectional area, suggesting the possibility that certain microbes could influence how the bone changes size with aging," said Dr. Kiel.

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