Research reveals how individual gut microbiota responses to high-carbohydrate diets influence glycemic sensitivity, paving the way for personalized nutrition.
By Priyanjana Pramanik, MSc.Reviewed by Lily Ramsey, LLMDec 11 2024 Research highlights the person-specific interplay between gut microbiota and high-carbohydrate diets, uncovering new insights into glycemic sensitivity and precision nutrition.
Background The impact of different macronutrient diets compared to low-carbohydrate ) on metabolic health has been widely debated. HC diets are often recommended due to their lower calorie density compared to fats, but concerns exist regarding their effects on blood sugar and insulin regulation. About the study The study aimed to explore the effects of high-carbohydrate and low-carbohydrate diets on gut microbiota and metabolic health, using several nutritional n-of-1 trials. They found that each participant's gut microbiota responded differently to the diets, creating distinct patterns.
The findings revealed that the microbiota's response to the HC diet could predict individual glycemic sensitivity, while the LC diet had less influence on blood glucose regulation. Gut microbiota was found to influence glycemic sensitivity, particularly under an HC diet. Principal component analysis revealed that certain microbial patterns could predict post-meal blood glucose responses, like the maximum glucose spike and the duration of high blood sugar.
Blood Blood Sugar Carbohydrate Diabetes Diet Glucose Glucose Metabolism Insulin Metabolism Nutrition Research
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