A team of Medical University of South Carolina researchers, led by Onder Albayram, Ph.D., reports in PNAS Nexus that they have discovered a novel protective response by which the brain naturally repairs itself after traumatic brain injury.
Mar 13 2024Medical University of South Carolina Findings could lead to drug treatments that improve the brain's ability to recover after concussions and prevent long-term brain disease.
For some people, repeated blows to the head can trigger a domino effect of secondary brain disease. They can develop chronic traumatic encephalopathy, a progressive type of dementia with no known cure. In fact, brain injuries are the No. 1 environmental risk factor for neurodegenerative brain diseases, such as Alzheimer's disease or other dementias, said Albayram.
This is the first study to show that the protein p17 does indeed play a crucial role in protecting the brain after repeated concussions. When researchers removed p17 in the brain cells of mice, they developed secondary disease after injury.
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