The way in which brains shrink in those who develop Alzheimer's disease follows no specific or uniform pattern, finds a new study by researchers at UCL and Radboud University in the Netherlands.
University College LondonOct 4 2024 The way in which brains shrink in those who develop Alzheimer's disease follows no specific or uniform pattern, finds a new study by researchers at UCL and Radboud University in the Netherlands.
The scientists say this new finding could enable more personalised medicines to be developed, targeting the specific range of brain areas affected in an individual. To overcome this, researchers at UCL used a normative modelling1 approach to gain insights into individual variability between Alzheimer's patients.
Related StoriesThe analysis showed that despite most participants starting out with similar-sized brains, different patterns of brain shrinkage were seen between individuals over time.
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