What can stressed yeast teach us about fundamental processes in the cell? A lot, according to scientists at the European Molecular Biology Laboratory (EMBL). The team studies, among other topics, how cells adapt to stress -- such as nutrient deprivation.
European Molecular Biology Laboratory Oct 9 2024 What can stressed yeast teach us about fundamental processes in the cell? A lot, according to scientists at the European Molecular Biology Laboratory . The team studies, among other topics, how cells adapt to stress -- such as nutrient deprivation. One of their favourite test subjects is the yeast species S. pombe, for centuries used in traditional brewing.
"One way for a cell to survive stressful conditions until better days is to reduce its use of energy to a minimum," explained Olivier Gemin, EIPOD Postdoctoral Fellow in the Mattei Team who led this new study. "Producing proteins demands a lot of energy, which can be saved by blocking ribosomes.""There could be different explanations," said Team Leader Simone Mattei.
"So far, ribosomes were known to interact with membranes only via their large subunit. But in starved cells, we saw that they do this upside-down, via the small subunit!" said Mattei.
Molecular Biology Yeast Cancer Cell Electron Medicine Membrane Mitochondria Research Stress
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