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The potassium chloride supplements are being recalled due to"failed dissolution," which can lead to high potassium levels. According to the United States Pharmacopeia , different supplements and medications undergo, which measures the"extent and rate of solution formation from a dosage form." Dissolution is also known as drug release, which is important for the treatment's effectiveness.
"For patients who require chronic use of potassium chloride extended-release oral capsules, especially in those patients with underlying comorbidities or conditions that cause altered excretory mechanisms for potassium such as hypertension, heart failure, or renal dysfunction, there is a reasonable probability of developing hyperkalemia that may lead to a range of severity of adverse events from being asymptomatic to more severe potential life threatening adverse events of hyperkalemia...
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