Tablet for breast cancer coming to NHS - what expert Manchester doctor says

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Tablet for breast cancer coming to NHS - what expert Manchester doctor says
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Elacestrant, also known as Korserdu, will be used to treat a specific kind of breast cancer

The NHS is set to introduce a new once-a-day tablet that targets advanced breast cancer, with around 1,100 patients in England expected to benefit from the treatment.

“The decision to make elacestrant available on the NHS marks a step change in the treatment of this challenging form of metastatic breast cancer,” said Dr Ciara O’Brien, Consultant Medical Oncologist at The Christie NHS Foundation Trust. “We now have an option that can overcome resistance to hormone therapy in breast cancer and keep the disease at bay for significantly longer compared to the standard of care shown in the trial.

She added: "Following its provisional rejection in October, crucially today’s decision means elacestrant will bring eligible patients hope of more precious time before their condition progresses to do the things that matter most to them, compared to treatments currently available." She concluded by emphasising the charity's commitment to ensuring access to vital treatments: "We remain tireless in our efforts to ensure every person with secondary breast cancer can access the vital treatments that they both so desperately need and deserve."

Helen Knight, NICE's director of medicines evaluation, commented: "The committee heard from the clinical and patient experts that people whose advanced breast cancer has an ESR1 mutation tend to have worse survival than people whose cancer doesn’t have this mutation.

However, the NHS spending watchdog said it was “ready to work with” manufacturer Menarini Stemline to address “uncertainty in evidence” surrounding the medication.

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