Adolescents with depression show heightened neural activity in response to parental criticism and are less positively impacted by parental praise, according to a study in Psychological Medicine. The research underscores the importance of psycho-education for parents and clinicians to better understand the unique emotional sensitivities of adolescents with depressive disorders.
By Neha MathurSep 6 2023Reviewed by Benedette Cuffari, M.Sc. In a recent article published in Psychological Medicine, researchers examine affective and neural responses to parental feedback in adolescents with depression.
Comparatively, criticism leads to increased neural activity in AI, ACC, and social cognition-related brain regions, including the dorsomedial prefrontal cortex , temporal poles, and inferior frontal gyrus in adolescents. The criteria for MDD or DEP diagnosis was based on the Kiddie-Schedule for Affective Disorders and Schizophrenia-Present and Lifetime Version . Other inclusion criteria included adolescents who recently started secondary school, lived with their parents and spoke Dutch fluently.
The researchers also determined whether adolescents with depression exhibited blunted or potentiated negative mood to parental criticism and abnormal neural activity in brain regions of the salience network, including AI and sgACC, as well as those involved in social cognition, such as the temporoparietal junction .
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