Protein mutation that causes Parkinson's may prevent another neurodegenerative disease umassamherst PLOSPathogens
Conceptualization, Formal analysis, Funding acquisition, Investigation, Supervision, Visualization, Writing – original draft, Writing – review & editingDepartment of Biology and Institute for Applied Life Sciences, University of Massachusetts Amherst; Amherst, Massachusetts, United States of
America, Institute for Neurodegenerative Diseases, Weill Institute for Neurosciences, University of California, San Francisco; San Francisco, California, United States of America, Department of Neurology, University of California, San Francisco; San Francisco, California, United States of America
United Kingdom Latest News, United Kingdom Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Bridget Jones author confirms fourth film is in the worksBREAKING NEWS: There's a fourth Bridget Jones film coming!
Read more »
Todd Howard says Bethesda's Indiana Jones game is 'a definite love letter' dating from 2009Rich is a games journalist with 15 years' experience, beginning his career on Edge magazine before working for a wide range of outlets, including Ars Technica, Eurogamer, GamesRadar+, Gamespot, the Guardian, IGN, the New Statesman, Polygon, and Vice. He was the editor of Kotaku UK, the UK arm of Kotaku, for three years before joining PC Gamer. He is the author of a Brief History of Video Games, a full history of the medium, which the Midwest Book Review described as '[a] must-read for serious minded game historians and curious video game connoisseurs alike.'
Read more »
Gut microbial flavonoid catabolite reverses fatty liver disease in miceGut microbial flavonoid catabolite reverses fatty liver disease in mice FattyLiver Hepatic Steatosis Liver LiverDisease flavonoid catabolite PNASNews ClevelandClinic
Read more »
House of Commons given low hygiene ratingWestminster City Council found mouse droppings in 19 separate locations around the House of Commons.
Read more »
Mansfield Woodhouse: Man arrested after burglaries on five roadsThe break-ins happened on the same day on five streets in Mansfield Woodhouse.
Read more »
INPP5D limits plaque formation and glial reactivity in the APP/PS1 mouse model of Alzheimer’s diseaseThe dual specificity lipid/protein phosphatase SHIP1 (encoded by the INPP5D gene) is enriched in myeloid cells. Single nucleotide polymorphisms (SNPs) in INPP5D coding and non-coding regions impact risk for developing late onset sporadic Alzheimer’s disease (LOAD). We present pathological analyses with spatial transcriptomics of mice with tamoxifen-sensitive microglial knockdown of Inpp5d and show exacerbated plaque pathology, plaque-associated microglial density, and altered gene expression around plaques, suggesting novel markers for plaque-associated reactive microglia. Competing Interest Statement SAL is a founder of AstronauTx Ltd. All other others declare no competing interests.
Read more »