The enigmatic 'brain microbiome' could play a role in neurological disease

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The enigmatic 'brain microbiome' could play a role in neurological disease
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Assistant Professor in Biomedical Sciences, Dublin City University.

The microbes that live in your gut are having their moment in the sun. Even if you haven't been following the research, you can't have missed the hundreds of adverts for probiotics and prebiotics, aimed at selling you products to keep your microbiome healthy.

It is also difficult to confirm the presence of microbes. The techniques used rely on analyzing foreign genetic material, which can be unreliable because these fragments of DNA could be the result of contamination. The previously mentioned 2013 study investigated whether microbes can invade the brains of people with HIV/AIDS. They compared brain tissue of people with HIV/AIDS to brain tissue of people without HIV/AIDS. Surprisingly, they found non-human genetic material that pointed to the presence of more than 173 types of bacteria and phages in the brains they studied.

A group of researchers from the University of Edinburgh compared the brains of people with Alzheimer's disease to healthy brains. The brains of people with Alzheimer's harboured more bacteria and fungi than healthy people. But they did find several species of fungi, bacteria and other microorganisms in healthy brains.

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